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Am J Respir Cell Mol Biol 38 : 509516 Reddy NM, Kleeberger SR, Kensler TW, Yamamoto M, Hassoun PM, Reddy SP 2009 Disruption of nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice

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Every peptide has a biological ceiling determined by receptor dynamics, and IGF-1 LR3 reaches that ceiling faster than most because of its extended half-life and high bioavailability