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doi: 10.1089/acm.2006.12.857

Previous studies have elucidated that AGE-RAGE pathway can affect bone homeostasis in multiple links, including biomineralization [57], osteogenesis [58], osteoclastic differentiation [59], etc

Both these methylation reactions are vital for growth and cell reproduction.910 Methionine, a sulfur-containing, essential amino acid, is a precursor of S-adenosylmethionine, a cofactor for one-carbon metabolism and the final methyl donor for the methylation of DNA, RNA, proteins, and phospholipids.11 The methionine synthase plays a paramount role in the synthesis of nitrogenous bases (purines and pyrimidines) involved in the formation of DNA

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