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It declines with age, and lower NAD+ is associated with slower metabolism and the changes we lump together as getting older. NNMT, meanwhile, consumes the raw materials your body uses to make NAD+ and in fat tissue, NNMT is often overexpressed, which can drag NAD+ down right where you least want a sluggish metabolism

If the muscle actually tenses during the injection, that can create more damage, inflammation and discomfort, says Dr

Research has shown that blocking NNMT can reduce lipogenesis by 50 to 70 percent in adipocytes compared to untreated controls