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van Geijlswijk IM, van der Heijden KB, Egberts AC, Korzilius HP, Smits MG

When IgG auto-Abs bind to a cell-surface target, they can activate complement or immune cell-mediated inflammatory responses directed against non-pathogenic tissue [20, 131]

These compounds penetrate the BBB in sufficient quantity to facilitate memory consolidation and retrieval in aged rats, and the scopolamine-induced amnesic rat model of AD, as measured employing the Morris water maze task of spatial memory [80]