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Furthermore, a recent study comparing global to muscle-specific knockout of SOD1 in mice demonstrated differentially altered neuromuscular integrity and dysregulated redox pathways in both the nerve and muscle of these animals (Sakellariou et al., 2018)

Although adverse reactions to intravenous, intramuscular or subcutaneous injection of 0.9% benzyl alcohol are not known to occur in man, experimental studies of small volume parenteral preparations containing 0.9% benzyl alcohol in several species of animals have indicated that an estimated intravenous dose up to 30 mL may be safely given to an adult without toxic effects