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Bradykinin and other members of the kallikrein-kinin system influence sperm motility and blood flow to the reproductive tract

Proc Natl Acad Sci USA 2007, 104(29):12175-12180

Paradoxically, exogenous lactate supplementation at moderate doses demonstrates protective effects

To regulate and guide the research and evaluation of nanomedicine, the Center for Drug Evaluation (CDE) of the China National Medical Products Administration formulated the Technical Guidelines for Nanomedicines Non-Clinical Safety Evaluation Research (Trial), which was issued in August 2021 ( in vitro or in vivo or an alternative toxicity testing method, and also reminded to carefully choose the dose and testing time period