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Thus, preliminary data from a phase 1b trial showed that use of cagrilintide and semaglutide in obese subjects resulted in greater weight loss than semaglutide alone, 17Percentage versus 10Percentage after 20 weeks [5]

The double-blind multicenter phase 3 trials STEP 1, 3, 4, 5 were conducted in adults (mean age 46.247.3 years), mostly females, with obesity or overweight with 1 weight-related complication (mean BMI 37.838.4 kg/m 2 ) and aimed to demonstrate the superiority of semaglutide 2.4 mg over placebo in BW lowering at 68 or 104 24 weeks as an adjunct to diet and physical activity 23

Food & Drug Administration, et al

If weight loss is the primary objective and your B12 is normal, dont expect injections to be the answer