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7,15,58,62,72,82 While skin cells can produce estrogens locally, the aromatase enzyme activity is 30-times lower compared to premenopausal ovarian tissue

For hNPCs stained with NRF2, signal was held to constant threshold across conditions and total area was normalized to DAPI area

To examine the capacity of WT and Mda5 -/- HSCs to repopulate lethally irradiated recipients, we sorted and transplanted 100 LSK-SLAM HSCs from young or aged WT or Mda5 -/- mice together with aged-matched CD45.1 competitors into CD45.1 lethally irradiated recipients, followed by whole bone marrow competitive secondary transplantations

GLUT 4, glucose transporter 4