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By 1993, Yoshiko Sonoda successfully purified the human CYP51A1 protein from liver microsomes and demonstrated its catalytic activity upon reconstitution with NADPH cytochrome P450 reductase (3.20 mmol per mg of protein /min), identifying its molecular weight as approximately 53 kDa [12]

IGF-1 is extensively researched across molecular biology, endocrinology, and metabolic science, particularly in studies focused on growth factor signalling, cellular proliferation, and tissue development

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