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I'm reading a very interesting book right now - 'Food Intelligence' by Julia Belluz and Kevin Hall PhD - which sheds light on some of this plus a lot of other science around the ultra-palatable UPFs, the addiction possibilities etc, which are of course largely under the umbrella of the companies you are referencing

However, designing a neutral tax is not as simple as it may seem given that vapor products are not all similar

Children of smokers have many more respiratory infections than do children of nonsmokers

Therefore, it is tricky to determine how much a bottle of e-liquid will last you as per factors mentioned, moreover, the juice will be affected not only by the most obvious one that is the size of the bottle, but also by the frequency you use it