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Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025

A., He, M., Vockley, J., Payne, N., Rhead, W., Hoppel, C., Spector, E., Gernert, K., and Gibson, K

Individual responses to vitamin D supplementation may vary, and they are determined by many factors, including baseline blood levels of vitamin D and the patients age

NAC has been shown to protect blood vessels, improve acne vulgaris, balance hormones in cases of polycystic ovarian syndrome (PCOS) or unexplained infertility and help to detoxify heavy metals