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To increase the specificity of NPs for GBM cells, scientists have investigated the use of ligands that can selectively attach to specific characteristics present on the external membrane of GBM cells(Yeini et al

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Complexation of propyl gallate with Fe2+

Colchicine, Neomycin, Aminosalicylic Acid, H2-blockers (e.g., Ranitidine), and Proton Pump Inhibitors (PPIs, e.g., Omeprazole): These oral medications can all interfere with the intestinal absorption of dietary B12, making the need for injectable B12 more pronounced