Shenzhen Loltree Technology Co., Ltd
The color also communicates the earthiness and honesty of the natural base materials giving it a distinct visual identity.
Without these enzymes, the body cannot break down and absorb nutrients effectively, resulting in steatorrhea the excretion of undigested fats in the stool, which is often foul-smelling and greasy
COCAINE: Physical and Mental Effects Overdose: Can be caused by as little as 1/50 gram Overwhelmingly intense stimulation Injury to heart and blood vessels More often not fataljust feels that way Severe reaction through in verse tolerance or kindling Miscellaneous Effects: Formication (itching from imaginary bugs) Dental erosion Seizures Gastrointestinal complications Cocaine Psychosis: Paranoid psychosis/schizophrenia caused by excess dopamine Can also activate genetic predisposition to schizophrenia COCAINE: Other Problems with Use Polydrug Use Alcohol, valium, heroin to take the edge off Adulteration & Contamination Cocaine at street level is almost always cut When injected, bacteria and viruses contaminate drugs and needles Hepatitis C rate for IV drug users is between 50% and 90% Compulsion Use for euphoria, boredom, peer pressure, curiosity, self-medication, escape from personal problems SMOKABLE COCAINE (CRACK & FREEBASE) Pharmacology of smokable Cocaine Began around 1981 Crack epidemic in 1986 Chemically crack is the same as freebase Delivered to the brain faster Ether converts cocaine to freebase Baking soda converts cocaine to crack Effects and Side Effects More intense than snorting or injecting Rush or euphoria last 5 20 minutes Replaced by the feeling of irritability and other negative emotions Always used in a binge pattern Chronic use include paranoia, intense cravings, depression, cocaine psychosis, high-risk sexual activity SMOKABLE COCAINE (CRACK & FREEBASE) Respiratory Effects Breathing problems Severe fever Chest pains Coughs Crack lung Hemorrhage Respiratory failure & death Aggravated by cigarette smoking Polydrug use Increases the potential for abuse of depressants SMOKABLE COCAINE (CRACK & FREEBASE) Overdose Mild-rapid heart beat Hyperventilation Fear of dying Kills several thousand a year due to Cardiac arrest Seizure Stroke Respiratory failure Severe hypothermia Consequences of Crack use Economic Social: abuse, family, legal, formation of sex trade Cocaine vs Amphetamines Cocaines duration is 40 minutes/ Meth is 4-6 hours Meth is cheaper Amphetamines Classification: Sympathomimetic agent Stimulate the release of sympathic neurotransmitters Activates the sympathetic nervous system that controls the fight or flight response Stimulates the reward/information center Street names: crank, ice, shabu, glass, clear History of Use First synthesized in 1887 Medically used in 1930s Treats narcolepsy & depression Used by students and truck drivers to stay awake Widely used in pill form during WW II Amphetamines History of Use Japanese epidemic continued after WW II 1970 6-8% of American population used prescribed amphetamines for weight loss Street speed chemists increased production of crank and crystal in late 1980s Ice highly potent smokable form used in 1990s and common use in Hawaii Recent development of ya ba in Thailand Amphetamines (Effects) Routes of Administration Snorting Intravenous Smoking Oral Neurochemistry Like cocaine, amphetamines increase levels of catecholamines by stimulating their release and blocking reuptake Unlike cocaine, amphetamines block metabolism Long term use alters the ability to produce vital neurotransmitters causing depression and taking mor to stay normal Amphetamines (Effects) Physical Effects Small to moderate doses cause Increased heart rate Raised body temperature Rapid respiration Higher blood pressure Extra energy Dilation of bronchial vessels Appetite suppression Meth users go on binges for 3, 4 or 10 days Long term use can cause sleep deprivation Heart & blood toxicity Severe malnutrition Bad or rotten teeth Tolerance is more pronounced Amphetamines (Effects) Mental & Emotional Effects Mild to intense euphoria / sense of wellbeing Prolong use leads to Irritability Paranoia Anxiety Confusion Poor judgement Hallucinations Delusions Can result in violent, suicidal & homicidal thoughts Antisocial behaviors Amphetamines (Effects) With abstinence, disturbed mental states such as amphetamine psychosis or depression can stop for some people Amphetamines release neurotransmitter that mimics sexual gratification Effects of Ice is greater on the brain than the respiratory and pulmonary system Results in more overdoses Greater mental side effects Longer detoxification Amphetamine Congeners/Lookalikes Methylphenidate (Ritalin) Most widely used Prescribed as mood elevator, narcolepsy and to treat Attention-deficit/hyperactivity disorder Diet Pills Only recommended for short-term use Careful monitoring by physician Long-term use associated with abuse Lookalikes Prescription drugs that contain ephedrine and pseudoephedrine (anti-asthmatics) Decongestants Caffeine Ephedra & ephedrine Miscellaneous Plant Stimulants Khat & methcathione Used in Arab and African countries Produces amphetamine like highs Insomnia, anorexia Chronic abuse cause exhaustion, violence & depression Methcathione: AKA ephedrone is synthesized in illegal labs in U.S
