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In accordance with this, it has been estimated that the steady-state concentration of superoxide in the mitochondrial matrix is 5- to 10- fold higher than in the cytosol ( Although ROS generated under physiological conditions are not harmful, and likely play a signaling role, toxic or pathological conditions that lead to an impairment of mitochondrial function can increase the release of ROS

Collectively, these findings indicate that astaxanthin supports synaptic plasticity through coordinated functional, structural, and molecular mechanisms, providing a mechanistic basis for its reported cognitive benefits (Grimmig et al., 2019

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Apr 4 2021;10(4)doi:10.3390/antiox10040561