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Most people have 23 pairs of chromosomes (46 total)

It is also important to be aware of symptoms that may suggest either worsening B12 deficiency or poorly controlled blood glucose, and to seek prompt medical advice if you experience: Persistent fatigue, breathlessness, or pallor (possible anaemia) Tingling, numbness, or weakness in the hands or feet (possible B12-related neuropathy) Unsteadiness when walking, or changes in memory or thinking (possible signs of more severe B12 deficiency requiring prompt assessment) Increased thirst, frequent urination, or unexplained weight loss (possible hyperglycaemia) If you think you may be experiencing a side effect from a medicine for example, symptoms of B12 deficiency that you believe may be related to metformin you or your healthcare professional can report this via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk

In general, acceptable as long as you have been medically evaluated and treated, have no current (within the last 6 months) heart related symptoms such as chest pain and have no limitations or restrictions on your normal daily activities

They may notice slight inflammation or measure pockets around the teeth that indicate the beginnings of periodontal issues