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If there is insufficient (or no) B12 in bloodstream, or it is not linking well with B12 at this stage, your MMA will increase in your bloodstream, and carry on increasing until B12 makes the journey and the required links

Expected timeline: Week 1 to 2: Initial reduction in inflammation and pain Week 2 to 4: Meaningful improvement in nerve-related symptoms (reduced radiating pain, improved sensation) Week 4 to 6: Continued structural healing, further functional improvement Post-protocol: Maximum benefits from a single course typically manifest by week 8 to 12 as tissue remodeling continues Use the SeekPeptides peptide calculator to determine exact dosing based on your vial concentration and desired dose

From there, it goes straight to the liver via the portal vein for whats called "first-pass metabolism." The liver is the body's detoxification center, and it's ruthless with foreign compounds, often breaking them down before they ever reach the rest of the body

Lister et al., 2009)