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The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

Shape-memory properties of PTK hydrogel To develop an implanted hydrogel used in minimally invasive surgery, the materials should be fixed as a temporary shape to be transferred through a narrow tube or syringe (mimic the arthroscope instrument) for facile manipulation and can be instantly recovered to the initial shape upon in vivo stimuli to fill the defect and further promote tissue regeneration

It was shown that DEFA1 displays a broad spectrum of antimicrobial activity against both fermenting and non-fermenting Gram-negative strains, against Gram-positive cocci, spore-forming bacilli, and the yeast Candida (C.) albicans