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Side effects and safety profile If clinical efficacy is where semaglutide dominates, safety is where AOD 9604 makes its strongest case

tuberculosis strains N0155 (lineage 2) and N1283 (lineage 4) 65 were grown in Middlebrook 7H9 broth (BD Difco) with 10% (v/v) oleic albumin dextrose catalase, 0.2% (v/v) glycerol, 0.05% tyloxapol (w/v) and 0.1 mM sodium propionate (ThermoFisher) to optical density at 600 nm (OD 600 ) = 0.6 (ref

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In the discovery paper, the anti-obesity efficacy of the molecule in mice exceeded that of a maximally effective dose of semaglutide, and mechanistic dissection attributed the additional effect specifically to increased energy expenditure combined with reduced food intake