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US Patent, Publication Number US7459145B2 Krister BCA, Linn BSR, Joakim EPB, Marie LM (2013) Compoisitons comprising polyglutamic acid nanoparticles and polypeptides such as cd40 agonists

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The Ozempic ladder reaches 2.0 mg weekly, but doubling from 1.0 to 2.0 mg added only about 0.23 percentage points of HbA1c reduction and 0.9 kg of weight loss. Beyond 1.0 mg, most of the added effect is on weight rather than glucose

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