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The fundamental metabolic defect of this syndrome was recognized as insulin resistance, but the pathophysiology of insulin resistance is not clarified as of yet

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Summary Keywords glucose-6-phosphate dehydrogenase, G6PD, immunity, immunometabolism, G6PD deficiency Citation Shah SS, Stone EF, Francis RO and Karafin MS (2024) The global role of G6PD in infection and immunity

Therefore, SDC-1 adapts to mechanical stimuli by modulating its interactions with actin and signaling intermediates