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The paucity of well-controlled clinical studies complicates the confirmation of whether the mechanisms identified in animals are directly applicable to humans

This approach can be more sustainable and gentler on the body, offering an alternative for those looking to support their glutathione levels naturally

Therapeutic strategies targeting this cycle -such as Nrf2 activators (sulforaphane), mitochondrial antioxidants (MitoQ), and AGE inhibitors (aminoguanidine)- highlight the dual role of OS as interventions early in DM, which can improve -cell function, while later-stage treatments primarily mitigate complications

For example ferrous sulfate is a common medication used to treat iron deficiency