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10.1155/2016/6147345 272 ZhangJ

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It is estimated that 25% of the global population has NAFLD, a number projected to continue to rise, and as it does, it is expected that more of these cases will progress to end-stage disease states requiring liver transplantation

For comparison, a mammalian cell line tolerated AF at concentration as high as 100 M for 5 d, while 5 M AF led to adult worm death in 24 h (Figure 6B)