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Moreover, the reactivity of GSH depends on the thiol (-SH) group of cysteine, which is the key feature for the biological activities of GSH

The second mechanism by which glutathione causes lightening of skin is inhibition of transfer of tyrosinase to premelanosomes for melanin synthesis.[] The third mechanism of tyrosinase inhibition is through its antioxidant effect as it scavenges the free radicals generated in the epidermis following UV light irradiation