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Since the ultimate goal of the project was to produce a clinically relevant molecule that could be delivered peripherally but still exhibit pro-cognitive/anti-dementia activity, the effectiveness of both the intraperitoneal and oral delivery routes of dihexa administration were determined using the scopolamine model

This is evidenced by the fact that endogenous -Syn levels lead to mitochondrial fragmentation (Kamp et al., 2010), and -Syn is forcibly delivered to the mitochondrial membrane, leading to mitochondrial fragmentation (Pozo et al., 2017)

Neil Riordans supervision, we developed techniques for isolating dendritic cells from whole blood and training them to respond to tumor antigens