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High-priority bacteria include fluoroquinolone-resistant Salmonella Typhi , vancomycin-resistant Enterococcus faecium , and MRSA

including , which catalyzes the methylation of tryptamine and structurally related compounds

With poorly controlled or severe disease, there is risk that extra-articular manifestations such as keratitis, pulmonary granulomas (rheumatoid nodules), pericarditis/pleuritis, small vessel vasculitis, and other non-specific extra-articular symptoms will develop