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Jayne Morgan, MD, a cardiologist and vice president of medical affairs at Hello Heart who specializes in womens health and cardiovascular research, said the first few cigarettes can in fact do the most damage

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This method considers factors like the estimated prevalence of e-cigarette use among secondary school students in Thailand (p=0.072, derived from a previous study 29 ), the desired margin of error (0.0072, representing 10% of the estimated proportion), the significance level (=0.05), and a cluster effect of 1.2 to account for students being nested within schools