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On the other hand, much like in the healthy rats (Figure 2A), we demonstrated that immediately after saline or BPC 157 administration, there was consistent normal eye background and normal presentation of the retinal and choroidal blood vessels (IS and IB)

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Careful dose titration is essential, starting with the lowest available dose (2.5 mg weekly) for initiation only, with increases every 4 weeks as tolerated to reach therapeutic doses per FDA labeling

Laboratory studies investigate its mechanisms at the cellular level, including receptor binding, signal transduction, and gene expression pathways