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Photodynamic therapy mechanisms, photosensitizers and combinations

doi:10.1046/j.1524-475X.1994.20406.x Leyden J, Stephens T, Finkey MB, Barkovic S, Schweiger D

Half-lives vary, some peptides degraded within minutes while others persist hours

COMT requires methyl groups to function, so when MTHFR mutations reduce methylation, neurotransmitters can accumulate rather than being efficiently cleared