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We wanted to capture the total production of CysLTs over a 48 h period rather than peak levels since newly synthesized CysLTs can continue to be produced and released for several hours after the initial stimulation

488,489,490 These inhibitors are capable of specifically targeting categories, subtypes, and structural domains, 491 potentially providing more pronounced benefits in terms of efficacy, safety, and tolerability

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As a strong antioxidant, BH4 maintains cell redox balance due to its powerful redox activity