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Prolonged UV exposure can induce matrix metalloproteinase-2 (MMP-2) and MMP-9 activation in basement membrane which can lead to collagen types 4 and 6 degradation and accumulation of more elastic fibers in melasma patients (Inomata et al., 2003)

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New serum + high-strength AHAs/BHAs on day one New serum + prescription retinoid on day one New serum + fragrance-heavy products if youre reactive How to pick the best one for your skin type (because its not one-size-fits-all) Oily or acne-prone skin: go water-based and non-comedogenic If you break out easily, look for a watery, fast-absorbing texture and avoid heavy oils, because clogged pores dont care about marketing