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When taken twice daily with Vitamin C, it effectively improves brightness, glow, and pigmentation within 48 weeks

For precise assessment, analytical techniques such as HPLC or mass spectrometry may be used

However, further studies are required to determine whether there is a direct correlation between NTHi disease prevalence and local geogenic iron oxide particulate levels among the broader population

All animal experiments were approved by the Committee on Animal Research at Tohoku University, and performed in agreement with the the Association for Research in Vision and Ophthalmology (ARVO) statement for the use of animals in ophthalmic and vision research and ARRIVE (Animals in Research: Reporting In Vivo Experiments) guidelines