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Trainer PJ, Drake WM, Katznelson L, Freda PU, Herman-Bonert V, van der Lely AJ, et al

This is based on studies involving TB-500 overexpression lentiviral vector in transfecting umbilical vein endothelial cells (HUVEC) and murine critical limb ischemia (CLI) models

10.3390/molecules23123305 448 TestaiL

Regardless, these non-inferiority data provide encouraging early evidence that NAD + raising therapies may be safe to use in cancer patients, though the heterogeneity of tumour types means that these studies should be interpreted with caution, and additional studies are needed in different cancer models