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Research shows that taking 3 g per day for six weeks can saturate keratinocytes in the skin, but taking more does not increase levels and may cause diarrhea

This is interesting because GPx-mediated reduction of FAHP could have different effects on COX or LOX activity depending on the accumulation of FAHP

Given these drawbacks, natural substances and nutraceuticals are gaining popularity throughout the world as potential supplements or substitutes for traditional treatments

This finding suggests that suppressing ferroptosis-related oxidative stress can partially mitigate the redox imbalance caused by SYNCRIP deficiency