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Medically reviewed by the Esthetic Clinic Medical Team.
Chemistry of GHK-Cu and Mechanism of Action GHK-Cu is a naturally occurring tripeptide that binds copper (II) ions with high affinity
Overview GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a tripeptide naturally present in human blood plasma, saliva, and urine
How Its Being Used Youll find GHK-Cu in: Topical serums (often post-laser or with microneedling) Compounded injectables and transdermal creams (off-label) PRP and hair regrowth protocols Common use cases: Post-surgical healing Cosmetic skin rejuvenation Hair regrowth (stacked with PRP or exosomes) Scar treatment Wound support The Evidence: Topical use has shown skin improvements in small cosmetic trials Gene expression and lab studies support repair, inflammation reduction, and mitochondrial protection relevant to cognitive decline Systemic use (injections, high-dose protocols) lacks long-term safety and outcome data Results are highly individual and confounded by other interventions (PRP, microneedling, exosomes, etc.) Is It Safe
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