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It is the second RNA aptamer and complement-targeted drug to receive FDA approval for this condition (125)

Regional decoupling of N-acetyl-aspartate and glutamate in schizophrenia

Materials and methods An extensive literature search was carried out independently on online databases (MEDLINE via PubMed, ISI Web of Science, and Scopus), by four reviewers (RMR, EM, LC, and CV) independently of each other, to identify relevant studies published between January 2005 and June 2025

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