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Cell Death and Differ (2003) 10(8):8649

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3.5 High mobility group box 1 and inflammatory signaling HMGB1, a nuclear protein, functions as a transcription factor and a DAMP that amplifies inflammatory responses ( + T cell activation and function

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BPC-157s selective modulation of inflammatory pathways may help shift the balance toward productive healing while limiting destructive chronic inflammation

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The active GSH rapidly oxidizes into the inactive GSSG

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