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Red blood cell inspired strategies for drug delivery: emerging concepts and new advances

GHK-Cu activates and upregulates SIRT1, an enzyme that regulates the function of other proteins by deacetylating them, reducing the activity of STAT3

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In the myocardium, fatty acid oxidation was inhibited, the glycolysis process was affected, the increase and circulation of TCA intermediates were in a poor status (the TCA metabolite ascending cycle is not smooth), and ATP production was decreased