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These compounds have been associated with a wide range of pharmacological activities, including antioxidative, radioprotective, antifatigue, hepatoprotective, immunomodulatory, neuroprotective, hypoglycemic, anti-osteoporotic, anticancer, and prebiotic activities [140]

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Berberine attenuates CCN2-induced IL-1 expression and prevents cartilage degradation in a rat model of osteoarthritis

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