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I think theres something wrong with peoples sensitivity scale some peoples immune system is so overactive that they react to nature, so I think the pathology lies with the patient, rather than the culprit being a piece of nature. Do certain strains make you sneeze

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The continual heating and cooling of the metal heating element as the system is used causes the vaporization of the trace metals found in the device resulting in the mobilization of small, toxic particles which are then inhaled [12]

Research can give you an option other that hormone therapy, for those that wish to avoid hormones