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The treatment of gout includes the changes in lifestyle, nutrition, and adjunctive therapies as well as different classes of drugs which are approved for lowering urate levels: xanthine oxidase inhibitors, uricosuric agents, uricase agents and some which are still under development, such are inhibitors of urate transporter, purine nucleoside phosphorylase and interleukin-1 antagonists (23)

These include: Chronic stress Stress causes the secretion of cortisol at high levels which is a catabolic steroid

Proc Natl Acad Sci USA 110:1862018625 Oliveira SH, Fonseca SG, Romao PR, Figueiredo F, Ferreira SH, Cunha FQ (1998) Microbicidal activity of eosinophils is associated with activation of the arginine-NO pathway

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