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Total disintegrations per minute of bound 3 H-Hinge were calculated based on machine counting efficiency

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Polymeric immunoglobulin receptor (pIgR), a component of secretory IgM which mediates the IgM transcytosis through the mucosal epithelial cells, also occupies the cleft in the IgM pentamer when bound, and therefore pIgR and AIM cannot bind IgM at the same time (Supplementary Fig

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