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Of note, the relative abundance of the Parasutterella genus, which was significantly enriched in both the vehicle- and 5A-1MQ-treated animals transitioned from WD to LD compared to both the WD and LD control groups, was observed to be significantly correlated (either positively or negatively) with 30 EWAT metabolites, both with and without outliers included

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[4] Red flag symptoms requiring immediate medical assessment include: progressive or worsening neurological symptoms, changes in vision, significant gait disturbance, or cognitive decline

When calorie intake drops, it is common to notice lower energy, more fatigue, and reduced motivation