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Packaging Trends: Over time, the 20 cigarettes per pack has become an industry norm, which, if changed, will be unpopular among consumers

Though this is not proven either way, it has been argued that given the amount of caffeine that can proportionally be included in an e-liquid, the amount of caffeine actually consumed via inhalation is not enough to produce a noticeable effect

At $13-$15 per pound, that works out to $0.03-$0.04 per cigaretteversus $0.30-$0.50 for factory cigarettes in most states

When predicting the age pattern of the excess risk of smoking on CVD outcomes using the fitted model, we did not include between-study heterogeneity to reduce uncertainty in the prediction