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Experimental studies demonstrate the ability of DHLA to scavenge peroxyl radicals in both lipophilic and hydrophilic environments, even in the absence of glutathione (GSH) and vitamin E

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The presence of multiple hgp genes may allow for selective expression of the Hgp with greatest affinity for the predominant host haemoglobin-haptoglobin phenotype, or alternatively as a strategy to evade the host immune response mounted against a particular Hgp-expressing population (Langlois and Delanghe, 1996)