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Search terms combined peptide agent names with musculoskeletal and perioperative keywords and included BPC-157, body protection compound, pentadecapeptide, thymosin beta-4, TB-500, TB500, GHK-Cu, copper tripeptide, growth hormone secretagogue, CJC-1295, ipamorelin, sermorelin, IGF-1, insulin-like growth factor, collagen peptide, tendon, ligament, cartilage, osteoarthritis, fracture healing, wound healing, perioperative, arthroplasty, total hip arthroplasty, total knee arthroplasty, and total joint arthroplasty

doi: 10.1186/1471-2334-11-200, 78 PalmaE.RecineN.DomeniciL.GiorginiM.PierangeliA.PaniciP

GHK-Cu is a naturally occurring peptide found in human plasma, saliva, and urine

Materials and Methods Search Strategy The literature review was conducted from 2000 to January 2021 using the PubMed, Medline and Web of Science databases