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These distinctions were central to its development as a targeted metabolic peptide and continue to inform its use as a pharmacological reference in fat-metabolism research today

BSO is an inhibitor of GSH synthase that has been used to deplete GSH in vitro , including in macrophages ( We analyzed the gene expression profile and identified patterns of LPS-induced genes that were inhibited by endogenous GSH or that, on the contrary, required GSH for their induction

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