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Whether you're exploring cognitive enhancement, neuroprotection, or synaptic repair mechanisms, the frequency decision should follow from what you're measuring and when you're measuring it
2004;24:255-275.doi:10.1146/annurev.nutr.23.011702.073054 Fraker PJ, King LE, Laakko T, VollmerTL
9) was used to generate a triple knockout line glyr1-1 hpr1-1 hpr2-3 as well as a triple mutant in the original suppressor background, shpr7 hpr2-3