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Psychopharmacology 216:245255 Dohrman DP, Reiter CK (2003) Ethanol modulates nicotine-induced upregulation of nAChRs

Even if cysteine S -conjugate -lyase is responsible for the synthesis of the highly reactive and cytotoxic thiol version of cisplatin ( Figure 1 ), the activation of cisplatin into a nephrotoxin relies on the three previous steps of the classical mercapturic acid pathway involving GSTs (GSH conjugation), GT (production of CisPt-cys-glu) and dipeptidase (production of CisPt-cys

Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity

Ultimately, by linking mechanistic insights to treatment development, these efforts hold promise for advancing more effective interventions and reducing the burden of this prevalent and debilitating condition