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Comparing DSIP with Epitalon and Orexin clarifies its role as a tool for investigating integrated neuroendocrine signaling, sleep architecture, and pathway-level interactions in experimental systems

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Importantly, the Gene Ontology (GO) categories of genes with altered expression in Tg mice overlapped with a significant number of GO categories of genes with altered expression in WT mice during ageing, even though the changes in gene expression in the hippocampus of Tg and WT mice did not always follow the same pattern

Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of -synucleinopathy