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No large-scale Phase III clinical trials have been completed in humans, and long-term safety data in human subjects is lacking

Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate

Healthcare providers can make Vitamin B12 therapy more effective by watching how patients react to the treatment

If you follow a vegan diet, have gut issues, or take certain medications, talk to your doctor about checking your B12 levels